140 Tablet:Role of Silymarin- Powerful antioxidant; Used to protect liver cells (and other cells in the body and brain) from toxins. The recommended dose is 140 mg 2-3 timesday. The four-year survival rate was 58 percent in the silymarin group and 39 percent in the placebo group. In people with liver disease, the typical dosage was higher, around 1.3 g/day of the standardized for 6 – 8 weeks (divided into 3 doses during the day). Search drug, interactions and image information in China, Hong Kong, Taiwan, Malaysia, Singapore, Philippines, Vietnam, Thailand, Indonesia, India & USA Common side effects of Silymarin : Abdominal bloating, diarrhea, flatulence, loss of appetite, nausea and stomach upset. The typical silymarin dosage used in most studies was ~420 mg/day divided into 2 or 3 doses. There were no side effects from silymarin.4 The combination of silybin and phosphatidylcholine in Liverprime is three times better absorbed than plain Silymarin. Side Effects & Safety When taken by mouth: N-acetyl cysteine is LIKELY SAFE for most adults. Beneficial in a number of diseases involving liver disease; Direction for use/Dosage: – Take as directed by the physician Subjects received 140 mg silymarin three times a day for 41 months. What is the dose of Legalon® (Silymarin) for a child? Brief stomach upset and mild allergies, but no serious side effects, have been reported. 70mg-capsule: 2 capsule/time x 3 times a day. In dogs given oral citicoline 1.5 g/kg daily for 6 months, no biochemical, neurological, or histological toxicity was found.1. Click here for full details on all the markets covered. Generic Name : Silymarin Pronunciation : SILL-ee-MAR-inn Latest prescription information about Silymarin. The dosage has not been established in pediatric patients. What is the dose of Legalon® (Silymarin) for an adult? MIMS products are highly valued and utilised widely across Australia by healthcare professionals in public and private acute care, primary care, aged care, community services – just to name a few. Silymarin is a fruit extract from the plant milk thistle that is claimed to be a free radical scavenger and to have hepatoprotectant properties; it has been used in various liver … 1. A 30-day study in rats found no toxicity at 150 mg/kg/day. Schauss AG, Somfai-Relle S, Financsek I, et al. It can cause nausea, vomiting, and diarrhea or constipation. References. How should Silymarin be used: It comes as a tablet, capsule, and syrup to take by mouth, with food. The reduced death rate among those taking silymarin was most pronounced in the alcoholic cirrhosis subgroup. Silymarin may intensify the effects of drugs that decrease blood sugar levels (hypoglycemic drugs). These results have been established by experimental and clinical trials. It may be unsafe for your child. 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